発表論文・著書・その他
[154] Membrane interaction and cytostatic properties of synthetic cobaltabisdicarbollide vesicles
M. Tarres, E. Canetta, E. Paul, J. Forbes, K. Azzouni, C. Vinas, C. Verdia-Baguena, A. Alcaraz, V. M. Aguilella, S. Tachikawa, H. Nakamura, A. M. Cioran1 F. Teixidor, A. J. Harwood, submitted.
[153] Diaryl-substituted ortho-carboranes as a new class of hypoxia inducible factor-1α inhibitors
H. Nakamura, L. Tazaki, D. Kanoh, S. Sato, H. H. Ban, J. Chem. Soc., Dalton Trans. (invited), accepted.
[152] Development of High Boron Content Liposomes and Their Promising Antitumor Effect for Neutron Capture Therapy
H. Nakamura, Yakugaku Zasshi (Review), in print (2013).
[151] A novel photodynamic therapy for drug resistant prostate cancer cells using porphyrus Envelope as a novel photosensitizer
M. Yamauchi, N. Honda, H. Hazama, S. Tachikawa, H. Nakamura, Y. Kaneda, K. Awazu, J. Biomed. Opt. accepted.
[150] Ligand-directed Selective Protein Modification Based on Local Single Electron Transfer Catalysis
S. Sato and H. Nakamura, Angew. Chem. Int. Ed. 52, 8681-8684 (2013).
[149] Synthesis and Biological Evaluation of ortho-Carborane Containing Benzoxazole as an Inhibitor of Hypoxia Inducible Factor (HIF)-1Transcriptional Activity
H. Nakamura, Y. Yasui, H. S. Ban, J. Organomet. Chem. (special issue) in print.
[148] Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors
H. Minegishi, S. Fukashiro, H. S. Ban, H. Nakamura, ACS Med. Chem. Lett. 4, 297-301 (2013). LINK
[147] Boron Cluster Lipid Liposomes as New Vehicles for Boron Delivery System of Neutron Capture Therapy
H. Nakamura, Future Med. Chem. (invited) 5(6), 715-730 (2013).
[146] Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their cholesterol conjugates
M. Bialek-Pietras, A. B. Olejniczak, S. Tachikawa, H. Nakamura, Z. J. Lesnikowski, Bioorg. Med. Chem. 21, 1136-1142 (2013). LINK
[145] Synthesis and Biological Evaluation of Diaryl-Substituted Carboranes as Inhibitors of Hypoxia Inducible Factor (HIF)-1 Transcriptional Activity
H. Minegishi, T. Matsukawa, H. Nakamura, ChemMedChem. 8, 265-271 (2013). LINK Selected as an Inside Cover Picture
[144] Development of Hypoxia-Inducible Factor (HIF)-1α Inhibitors: Effect of ortho-Carborane Substituents on HIF Transcriptional -Activity under Hypoxia
H. Nakamura, Y. Yasui, M. Maruyama, H. Minegishi, H. S. Ban, S. Sato, Bioorg. Med. Chem. Lett. 23, 1455-1461 (2013). LINK
[143] Development of High Boron Content Liposomes and Their Promising Antitumor Effect for Neutron Capture Therapy of Cancers
H. Koganei, M. Ueno, S. Tachikawa, L. Tasaki, H. S. Ban, M. Suzuki, K. Shiraishi, K. Kawano, M. Yokoyama, Y. Maitani, K. Ono, H. Nakamura, Bioconjugate Chem. 24, 124-132 (2013). LINK
[142] HSP60 as a drug target
H. Nakamura and H. Minegishi, Curr. Pharm. Des., (Review) 19(3), 441-451 (2013). LINK
[141] 蛍光標識ホウ素脂質の開発とリポソーム化による細胞内イメージング
上田記子、小金井逸人、上野学、立川将士、鈴木実、小野公二、中村浩之、 Progress in Drug Delivery System XXI, 68-73 (2012).
[140] Synthesis and biological evaluation of furylindazoles as hypoxia inducible factor (HIF)-1α inhibitors
A. Takeuchi, M. Hori, S. Sato, H. S. Ban, T. Kuchimaru, S. Kizaka-Kondoh, T. Yamori, H. Nakamura, Med. Chem. Commun. 3, 1455-1461 (2012). LINK
[139] Discovery of 1-[4-(N-Benzylamino)phenyl]-3-phenylurea Derivatives as Non-Peptidic Selective SUMO-Sentrin Specific Protease (SENP)1 Inhibitors
M. Uno, Y. Koma, H. S. Ban, H. Nakamura, Bioorg. Med. Chem. Lett. 22, 5169-5173 (2012). LINK
[138] Copper(I)-catalysed deacetylenative cross-coupling reaction of terminal alkynes with propargylic amines via C(sp)-C(sp3) bond cleavage
Y. Kim and H. Nakamura, Synlett, 23, 1686-1690 (2012). LINK
[137] In vitro investigation of efficient Photodynamic Therapy using non-viral vector; Hemagglutinating virus of Japan envelope
N. Fujimoto, M. Sakai, K. Ishii, H. Nakamura, Y. Kaneda, K. Awazu, J. Biomed. Opt., 17(7), 078002 (Jul 17, 2012). LINK
[136] Identification of heat shock protein 60 as the regulator of the hypoxia-inducible factor sub-unit HIF-1α
H. S. Ban, K. Shimizu, H. Minegishi, H. Nakamura, Pure Appl. Chem., 84(11), 2325-2337 (2012). LINK
[135] Synthesis and biological evaluation of boronic acid containing phenstatin analogues
H. Nakamura, H. Kuroda, H. Minegishi, ARKIVOC, 2012(vii), 79-87.LINK
[134] Zinc(II)-Catalyzed Redox Cross-Dehydrogenative Coupling of Propargylic Amines and Terminal Alkynes for Synthesis of N-Tethered 1,6-Enynes
T. Sugiishi, H. Nakamura, J. Am. Chem. Soc.134, 2504-2507 (2012).LINK
[133] Design and synthesis of fluorescence-labeled closo-dodecaborate lipid: liposome formation and in vitro and in vivo imaging targeting to tumor for boron neutron capture therapy
H. Nakamura, N. Ueda, H. B. Ban, M. Ueno, S. Tachikawa, Org. Biomol. Chem. 10, 1374-1380 (2012).LINK
[132] 今後、治療の多様化に適応できるホウ素薬剤の開発を
中村浩之, エネルギーレビュー, 特集：岐路に立つホウ素中性子捕捉療法, 31(11), 17-18 (2011). LINK
[131] Facile Synthesis of 4-Substituted 3,4-Dihydro-1H-2,1,3-Benzothiadiazine 2,2-Dioxides
C.-H Lee, G. F. Jin, H. W. Lim, E. H. Yang, J.-D. Lee, H. Nakamura, H. S. Ban, S. O. Kang, Heteroatom Chem. 22, 192-197 (2011). LINK
[130] Copper(I)-Catalyzed Deacetylenative Coupling of Propargylic Amines: An Efficient Synthesis of Symmetric 1,4-Diamino-2-butynes
Y. Kim and H. Nakamura, Chem. Eur. J. 17, 12561-12563 (2011). LINK
[129] Discovery of ortho-Carborane-Conjugated Triazines as Selective Topoisomerase I/II Inhibitors
H. Nakamura, A. Shoji, A. Takeuchi, H. B. Ban, J.-D. Lee, T. Yamori, S. O. Kang, Aust. J. Chem. 64(11), 1430-1437 (2011). LINK
[128] Amphiphilic Allylation of Arylidene-1,3-oxazol-5(4H)-one Using Bis-π-allylpalladium Complexes: An Approach to Synthesis of Cyclohexyl and Cyclohexenyl α-Amino Acid
A. R. Genady, H. Nakamura, Org. Biomol. Chem. 9, 7180-7189 (2011). LINK
[127] Biological evaluation of dopamine analogues containing phenylboronic acid group as new boron carriers
Y. Ito, T. Mizuno, K. Yoshino, H.S. Ban, H. Nakamura, J. Hiratsuka, A. Ishikawa, H. Ohki, Appl. Radiat. Isotope. 69(12), 1771-1773 (2011). LINK
[126] m-Carborane-Based Chiral NBN Pincer-Metal Complexes: Synthesis, Structure, and Application in Asymmetric Catalysis
M. E. El-Zaria, H. Arii, H. Nakamura, Inorg. Chem. 50(9), 4149-4161 (2011). LINK
[125] Hypoxia-Inducible Factor Inhibitors: A Survey of Recent Patented Compounds (2004-2010)
H. S. Ban, Y. Uto, H. Nakamura, Exp. Opin. Ther. Patents, (invited) 21(2), 131-146 (2011). LINK
[124] Catalytic Reactions of Bis-π-allylpalladium Generated from Allyltrifluoroborate
H. Nakamura, K. Shimizu, Tetrahedron Lett. 52(3), 426-429 (2011). LINK
[123] Salicylate restores transport function and anion exchanger activity of missense pendrin mutations
K. Ishihara, S. Okuyama, S. Kumano, K. Iida, H. Hamana, M. Murakoshi, T. Kobayashi, S. Usami, K. Ikeda, Y. Haga, K. Tsumoto, H. Nakamura, N. Hirasawa, H. Wada, Hearing Res. 270, 110-118 (2010). LINK
[122] ホウ素の中性子捕捉反応を利用した低侵襲細胞選択的放射線療法
中村浩之, Yakugaku Zasshi 130, 1687-1694 (2010). LINK
[121] Selective Inhibition of EGFR and VEGFR2 Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines
H. Nakamura, R. Horikoshi, T. Usui, H. S. Ban, Med. Chem. Commun.1, 282-286 (2010). LINK
One of the top ten accessed articles from the online version of MedChemComm in the Royal Cemical Society journals!
[120] Identification of HSP60 as a Primary Target of ortho-Carboranylphenoxyacetanilide, an HIF-1α Inhibitor
H. S. Ban, K. Shimizu, H. Minegishi, H. Nakamura, J. Am. Chem. Soc.132(34), 11870-11871(2010).LINK
[119] リポソームを用いる中性子捕捉治療
上野学、潘鉉承、中村浩之 Drug Delivery System, 25(5), 474-482 (2010).LINK
[118] Undecahydro-closo-dodecaborates as good leaving groups in organic synthesis: Generation of substituted styrenes via elimination of arylethyl dodecaborates
A. R. Genady, H. Nakamura, Org. Biomol. Chem.8, 4427-4435(2010). LINK
[117] 中性子捕捉治療のためのナノカプセル型ホウ素薬剤送達システム（BDS）の開発
中村浩之, Pharm. Tech. Japan (invited) 26, 1005-1012 (2010). LINK
[116] Discovery of Carboranes as Inducers of 20S Proteasome Activity
H. S. Ban, H. Minegishi, K. Shimizu, M. Maruyama, Y. Yasui, H. Nakamura, ChemMedChem, 5(8), 1236-1241 (2010). LINK
[115] Synthesis of triazolyl methyl-substituted amino- and oxy-undecahydrododecaborates for potential application in boron neutron capture therapy
M. E. El-Zaria, A. R. Genady, H. Nakamura, New J. Chem. 34, 1612-1622 (2010). LINK
[114] Copper(I)-Catalyzed Substitution Reactions of Propargylic Amines: Importance of Csp-Csp3 Bond Cleavage in Generation of Iminium Intermediates
T. Sugiishi, A. Kimura, H. Nakamura, J. Am. Chem. Soc.132 (15), 5332-5333 (2010) LINK
[113] Suppression of hypoxia-induced HIF-1α accumulation by VEGFR inhibitors: different profiles of AAL993 versus SU5416 and KRN633
H. S. Ban, M. Uno, H. Nakamura, Cancer Lett. 296(1), 17-26 (2010). LINK
[112] closo-Dodecaborate Lipid Liposomes as New Boron Delivery Vehicles for Neutron Capture Therapy of Cancers
M. Ueno, H. S. Ban, K. Nakai, Y. Kaneda, A. Matsumura, H. Nakamura, Bioorg. Med. Chem. 18, 3059-3065 (2010). LINK
[111] Boron-Containing Phenoxyacetanilide Derivatives as Hypoxia-Inducible Factor (HIF)-1α Inhibitors
K. Shimizu, M. Maruyama, Y. Yasui, H. Minegishi, H. S. Ban, H. Nakamura, Bioorg. Med. Chem. Lett. 20(4), 1453-1456 (2010). LINK
[110] Enhancement of EGFR Tyrosine Kinase Inhibition by C-C Multiple Bonds-Containing Anilinoquinazolines
H. S. Ban, Y. Tanaka, W. Nabeyama, M. Hatori, H. Nakamura, Bioorg. Med. Chem. 18(2), 870-879 (2010).LINK
[109] Boron-Containing Protoporphyrin IX Derivatives and Their Modification for Boron Neutron Capture Therapy: Synthesis, Characterization, and Comparative In Vitro Toxicity Evaluation
M. E. El-Zaria, H. S. Ban, H. Nakamura, Chem. Eur. J. 16(5), 1543-1552 (2010). LINK
[108] New Strategy for Synthesis of Mercaptoundecahydrododecaborate Derivatives via Click Chemistry: Possible Boron Carriers and Visualization in Cells for Neutron Capture Therapy
M. E. El-Zaria, H. Nakamura, Inorg. Chem. 48(24), 11896-11902 (2009). LINK
[107] New Types of Potential BNCT Agents, o-Carboranyl Aminoalcohols
C.-H. Lee, G. F. Jin, J. G. Joung, J.-D. Lee, H. S. Ban, H. Nakamura, J.-K. Cho, S. O. Kang, Tetrahedron Lett. 50(24), 2960-2963 (2009).LINK
[106] Discovery of Boron-Conjugated 4-Anilinoquinazoline as a Prolonged Inhibitor of EGFR Tyrosine Kinase
H. S. Ban, T. Usui, W. Nabeyama, H. Morita, K. Fukuzawa, H. Nakamura,Org. Biomol. Chem. 7(21), 4415-4427 (2009). LINK
[105] Synthesis and Biological Evaluation of Boron Peptide Analogues of Belactosin C as Proteasome Inhibitors
H. Nakamura, M. Watanabe, H. S. Ban, A. Asai, Bioorg. Med. Chem. Lett. 19(12), 3220-3224 (2009). LINK
[104] Discovery of 1-[4-(N-Benzylamino)phenyl]-3-phenylurea Derivatives as a New Class of Hypoxia-Inducible Factor-1α Inhibitors
M. Uno, H. S. Ban, H. Nakamura, Bioorg. Med. Chem. Lett. 19(12), 3166-3169 (2009). LINK
[103] Development of Boron Nano Capsules for Neutron Capture Therapy
H. Nakamura, M. Ueno, H. S. Ban, K. Nakai, K. Tsuruta, Y. Kaneda, A. Matsumura, Appl. Radiat. Isotope. 67. S84-S87 (2009).LINK
[102] Development of Boron Delivery System for Neutron Capture Therapy of Cancer
H. Nakamura, Progress in Drug Delivery System XVII, 19-24 (2008).
[101] Synthesis of Allenes via CuBr-catalyzed Homologation of Alk-1-ynes Accelerated by Microwave
H. Nakamura, T. Sugiishi, Y. Tanaka, Tetrahedron Lett. 49(50), 7230-7233 (2008). LINK
[100] Phase-Vanishing Methods Based on Fluorous Phase Screen.  A Simple Way for Efficient Execution of Organic Synthesis
I. Ryu, H. Matsubara, H. Nakamura, D. P. Curran, Chem. Rec. 8(6), 351-363 (2008). LINK
[99] Molecular Effects of the Tissue-Nonspecific Alkaline Phosphatase Gene Polymorphism (787T>C) Associated with Bone Mineral Density
N. Sogabe, K. Oda, H. Nakamura, H. Orimo, H. Watanabe, T. Hosoi, M. Goseki-Sone, Biomed. Res. 29(4), 213-219 (2008). LINK
[98] がん中性子捕捉療法と次世代ホウ素デリバリーシステム
中村浩之、臨床血液 (invited), 49(5) 294-301 (2008). LINK
[97] Allene as an Alternative Functional Group for Drug Design: Effect of C-C Multiple Bonds Conjugated with Quinazolines on EGFR Tyrosine Kinase Inhibition
H. S. Ban, S. Onagi, M. Uno, W. Nabeyama, H. Nakamura, ChemMedChem. 3, 1094-1103 (2008). LINK
[96] Synthesis of closo-Dodecaboryl Lipids and Their Liposomal Formation for Boron Neutron Capture Therapy
H. Nakamura, J.-D. Lee, M. Ueno, Y. Miyajima, H. S. Ban, NanoBiotechnology (invited), 3, 135-145 (2007). LINK
[95] Synthesis of 1,2-Dihydroisoquinolines via Palladium (0)-Catalysed Addition-Cycloaddition of Pronucleophiles to ortho-Alkynylaldimines
H. Nakamura, H. Saito, M. Nanjo, Tetrahedron Lett.49, 2697-2700 (2008). LINK
[94] Synthesis of Mono- and 1,3-Disubstituted Allenes from Propargylic Amines via Palladium-Catalysed Hydride-Transfer Reaction
H. Nakamura, M. Ishikura, T. Sugiishi, T. Kamakura, J-F. Biellmann, Org. Biomol. Chem. 6, 1471-1477 (2008). LINK
[93] De novo Design and Synthesis of N-Benzylanilines as New Candidates for VEGFR Tyrosine Kinase Inhibitors
M. Uno, H. S. Ban, W. Nabeyama, H. Nakamura, Org. Biomol. Chem. 6, 979-981 (2008). LINK
Selected in the RSC's Chemical Biology Research Articles!
[92] Liposomal Boron Delivery System for Neutron Capture Therapy
H. Nakamura, YAKUGAKU ZASSHI (Review)128, 193-208 (2008). LINK
[91] Synthesis and Characterization of Polar Functional Group Substituted Mono- and Bis-(o-carboranyl)-1,3,5-triazine Derivatives
C.-H. Lee, G. F. Jin, J. H. Yoon, Y. J. Jung, J.-D. Lee, S. Cho, H. Nakamura, S. O. Kang, Tetrahedron Lett. 49, 159-164 (2008). LINK
[90] Discovery of Indenopyrazoles as EGFR and VEGFR-2 Tyrosine Kinase Inhibitors by in silico High-Throughput Screening
T. Usui, H. S. Ban, J. Kawada, T. Hirokawa, H. Nakamura, Bioorg. Med. Chem. Lett.18, 285-288 (2008). LINK
[89] Synthesis of Dodecaborate-Conjugated Cholesterols for Efficient Boron Delivery in Neutron Capture Therapy
H. Nakamura, M. Ueno, J.-D. Lee, H. S. Ban, E. Justus, P. Fan, D. Gabel, Tetrahedron Lett. 48, 3151-3154 (2007). LINK
[88] Synthesis of Boron Cluster Lipids: closo-Dodecaborate as an Alternative Hydrophilic Function of Boronated Liposomes for Neutron Capture Therapy
J.-D. Lee, M. Ueno, Y. Miyajima, H. Nakamura, Org. Lett. 9, 323-326 (2007). LINK
[87] Synthesis and Liposome Formation of B-10 Enriched B12H11S-Substituted Lipid for Boron Delivery System on BNCT
J-D. Lee, H. Nakamura, Advances in Neutron Capture Therapy, 238-241 (2006).
[86] Transferrin-Loaded nido-Carborane Liposomes: Synthesis and Intracellular Targeting to Solid Tumors for Boron Neutron Capture Therapy
H. Nakamura, Y. Miyajima, Y. Kuwata, S. Masunaga, K. Ono, K. Maruyama, Advances in Neutron Capture Therapy, 195-198 (2006).
[85] A New NEDO Reseach Project Toward Hospital Based Accelerator BNCT using Advanced DDS system
A. Matsumura, Y. Mori, Y. Kaneda, K. Hashimoto, K. Nakai, T. Yamamoto, H. Nakamura, K. Akamatsu, T. Asano,S. Lee, Y. Sakurai, H. Kumada, K. Yamamoto, Y. Shibata, T. Shibata, T. Nakahara, M. Mutoh, H. Sakae, Y. Yuasa,Y. Satoh, H. Sakurabata, S. Muraki, T. Nagayama, Advances in Neutron Capture Therapy, 74-76 (2006).
[84] Selective Inhibition of EGFR and VEGER Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines
H. Nakamura, T. Usui, R. Horikoshi, W. Nabeyama, H. S. Ban, YAKUGAKU ZASSHI, 126, 164-165 (2006).
[83] Synthesis and Biological Evaluation of Benzamides and Benzamidines As Selective Inhibitors of VEGFR Tyrosine Kinases
H. Nakamura, Y. Sasaki, M. Uno, T. Yoshikawa, T. Asano, H. S. Ban, H. Fukazawa, M. Shibuya, Y. Uehara, Bioorg. Med. Chem. Lett. 16, 5127-5131 (2006). LINK
[82] Transferrin-Loaded nido-Carborane Liposome: Synthesis and Intracellular Targeting to Solid Tumors for Boron Neutron Capture Therapy
Y. Miyajima, H. Nakamura, Y. Kuwata, J-D. Lee, S. Masunaga, K. Ono, K. Maruyama, Bioconjugate Chem. 17, 1310-1320 (2006). LINK
Highlighted in the NIH Alliance for Nanotechnology in Cancer, Nanotech, 2006, September 5.
[81] Synthesis and Biological Evaluation of Boron Containing cis-Stilbenes as Apoptotic Tubulin Polymerization Inhibitors
H. Nakamura, H. Kuroda, H. Saito, R. Suzuki, T. Yamori, K. Maruyama, T. Haga, ChemMedChem 1, 729-740 (2006). LINK
[80] 1,2-Bis(diphenylphosphino)carborane As a Dual Mode Ligand for both the Sonogashira Coupling and Hydride-Transfer Steps in Palladium-Catalyzed One-Pot Synthesis of Allenes from Aryl Iodides
H.Nakamura, T. Kamakura, S. Onagi, Org. Lett. 8, 2095-2098 (2006). LINK

[79]

 Synthesis and Biological Evaluation of Allenic Quinazolines Using Palladium-Catalyzed Hydride-Transfer Reaction
H. Nakamura, S. Onagi, Tetrahedron Lett. 47, 2539-2542 (2006). LINK
[78] Synthesis of Water Soluble THIQ Derivatives as Potential Boron Neutron Capture Therapy Agents: N-Functionalized o-Carboranylmethylbenzopiperidines
C-H. Lee, J. M. Oh, J-D. Lee, H. Nakamura, S. O. Kang, Synlett, 275-278 (2006). LINK
[77] Synthesis of Ene-Allenes via Palladium-Catalyzed Hydride-Transfer Reaction of Propargylic Amines under Mild Conditions
H. Nakamura, S. Tashiro, T. Kamakura, Tetrahedron Lett. 28, 8333-8336 (2005). LINK
[76] ドッキングシミュレーションによるキナーゼ阻害剤の分子設計
中村浩之, ファルマシア, 最前線, 12月号, 749-753 (2005).
[75] Transferrin-Conjugated Boron Liposomes as a Potent Boron Delivery System for Neutron Capture Therapy
H. Nakamura, Y. Miyajima, Y. Kuwata, S. Masunaga, K. Ono, K. Maruyama, Progress in Drug Delivery System XIV, 45-53 (2005).
[74] Synthesis of Hetrocyclic Allenes via Palladium-Catalyzed Hydride-Transfer Reaction of Propargylic Amines
H. Nakamura, S. Onagi, T. Kamakura, J. Org. Chem. 70, 2359-2360 (2005). LINK
[73] Functional Analysis of the Single-nucleotide Polymorphism (787T>C) in Tissue-nonspecific Alkaline Phosphatase Gene Associated with Born Mineral Density
M. Goseki-Sone, N. Sogabe, M. Fukushi-Irie, L. Mizoi, H. Orimo, T. Suzuki, H. Nakamura, H. Orimo, T. Hosoi, J. Born Miner. Res. 20, 773-782 (2005). LINK
[72] Synthesis and in vivo biodistribution of BPA-Gd-DTPA Complex as a Potential MRI Contrast Carrier for Neutron Capture Thereapy
K. Takahashi, H. Nakamura, S. Fukumoto, K. Yamamoto, H. Fukuda, A. Matsumura, Y. Yamamoto, Bioorg. Med. Chem. 13, 735-743, (2005). LINK
[71] trans-1,2-Dibromocyclohexane. The Phase Vanishing Bromination with FC-72 as a Screen Phase
I. Ryu, H. Matsubara, H. Nakamura, D. P. Curran, In The Handbook of Fluorous Chemistry, J. A. Gladysz, D. P. Curran, I. T. Horvath, Eds. Wiley-VCH, Weinheim, 2004, Ch 11.46, pp 468-470. LINK
[70] Synthesis and Vesicle Formation of a nido-Carborane Cluster Lipid for Boron Neutron Capture Therapy
H. Nakamura, Y. Miyajima T. Takei, S. Kasaoka, K. Maruyama, Progress in Drug Delivery System XIII, 85-94 (2004). LINK
[69] Synthesis of 1,2-dihydroisoquinolines via the reaction of ortho-alkynylarylimines with bis-π-allylpalladium
M. Ohtaka, H. Nakamura, Y. Yamamoto, Tetrahedron Lett. 45, 7339-7341 (2004). LINK
[68] Synthesis and Vesicle Formation of a nido-Carborane Cluster Lipid for Boron Neutron Capture Therapy.
H. Nakamura, Y. Miyajima T. Takei, S. Kasaoka, K. Maruyama, Chem. Commun. 1910-1911 (2004). LINK
Selected as “Hot Paper” and introduced in the RSC’s Chemical Science, 2004, 1, C65.
[67] Synthesis of N-Functionalized 3,4-o-Carboranylenepiperidines as Potential Boron Neutron Capture Therapy Agents
C-H. Lee, I. D. Yang, J-D. Lee, H. Nakamura, S-O. Kang. Synlett. 1799-1801 (2004). LINK
[66] Benzamides and Benzamidines as Specific Inhibitors of Epidermal Growth Factor Receptor and v-Src Protein Tyrosine Kinases
T. Asano, T. Yoshikawa, T. Usui, H. Yamamoto, Y. Yamamoto, Y. Uehara, H. Nakamura. Bioorg. Med. Chem. 12, 3529-3542 (2004). LINK
[65] Synthesis of Allenes via Palladium-Catalyzed Hydrogen Transfer Reactions: Propargylic Amines As an Allenyl Anion Equivalent
H. Nakamura, T. Kamakura, M. Ishikura, J-F. Biellmann. J. Am. Chem. Soc.126, 5958-5959 (2004). LINK
[64] Synthesis and Biological Evaluation of Benzamindes and Benzamidines: Structural Requirement of a Pyrimidine Ring for Inhibition of EGFR Tyrosine Kinase
T. Asano, T. Yoshikawa, H. Nakamura, Y. Uehara, Y. Yamamoto, Bioorg. Med. Chem. Lett. 14, 2299-2302 (2004). LINK
[63] Design, Synthesis, and Biological Evaluation of Aminoboronic Acids as Growth Factor Receptor Inhibitors for EGFR and Flt-1 Tyrosine Kinases
T. Asano, H. Nakamura, Y. Uehara, Y. Yamamoto, ChemBioChem, 5, 483-490 (2004). LINK
[62] o-Carboranyl Derivatives of 1,3,5-s-Triazines: Structures, Properties, and in vitro Activities
H-G. Lim, J-D. Lee, Y-J. Lee, C-H. Lee, J. Ko, H. Nakamura, S-O. Kang, Appl. Organometal. Chem. 17, 539-548 (2003). LINK
[61] A Fluorous Solvent as a New Phase-Screen Medium between Reagents and Reactants in the Bromination and Chlorination of Alcohols
H. Nakamura, T. Usui, H. Kuroda, I. Ryu, H. Matsubara, S. Yasuda, D. P. Curran, Org. Lett. 5, 1167-1169 (2003). LINK
[60] Phase-Vanishing Reactions that Use Fluorous Media as a Phase Screen. Facile, Controlled Bromination of Alkenes by Dibromine and Dealkylation of Aromatic Ethers by Boron Tribromide
I. Ryu, H. Matsubara, S. Yasuda, H. Nakamura, D. P. Curran, J. Am. Chem. Soc. 124, 12946-12947 (2002) LINK
[59] Tandem Nucleophilic Allylation-Alkoxyallylation of Alkynylaldehydes via Amphiphilic Bis-p-allylapalladium Complexes
H. Nakamura, M. Ohtaka, Y. Yamamoto, Tetrahedron Lett. 43, 7631-7633 (2002). LINK
[58]  A Convenient Synthesis of the Novel carboranyl-substituted Tetrahydroisoquinolines: Application to the Biologically Active Agent for BNCT
Lee, J-D.; Lee, C-H.: , Nakamura, H.; Ko, J.; Kang, S-O. Tetrahedron Lett. 43, 5483-5486 (2002). LINK
[57] Palladium-Catalyzed Aminoallylation of Activated Olefins with Allylic Halides and Certain Amines
K. Aoyagi, H. Nakamura, Y. Yamamoto, J. Org. Chem. 67, 5977-5980 (2002). LINK
[56] Nucleophilic Allylation-Heterocyclization via Bis-p-allylpalladium Complexes: Synthesis of Five- and Six-Membered Heterocycles
Bao, H. Nakamura, A. Inoue, Y. Yamamoto, Chem. Lett. 158-159 (2002). LINK
[55] o-Carboranyl derivatives of 1,3,5-triazines
H.-G. Lim, J.-D. Lee, Y.-J. Lee, C.-H. Lee, H. Nakamura, S.-H. C.-H. Lee, B. Jun, J. Ko, S.-O. Kang, Research and Development in Neutron Capture Therapy, W. Sauerwein, R. Moss, A. Wittig, Eds. p-37-42, Monduzzi, Bologna (2002).
[54] Synthesis of carboranyl derivatives of a tetrahydroisoquinoline.
J-D. Lee, C-H. Lee, H. Nakamura, S-H. Lee, C-H. Lee, B. Jun, J. Ko, S-O. Kang, Research and Development in Neutron Capture Therapy, W. Sauerwein, R. Moss, A. Wittig, Eds. p-31-35, Monduzzi, Bologna (2002).
[53] Novel Carboranes with a DNA Binding Unit for the Treatment of Cancer by Boron Neutron Capture Therapy
L.F. Tietze, U. Griesbach, U. Bothe, H. Nakamura, Y. Yamamoto, ChemBioChem, 3, 219-225 (2002). LINK
[52] Formation of Cyclic Ethers via the Palladium-Catalyzed Cycloaddition of Activated Olefins with Allylic Carbonates Having a Hydroxy Group at the Terminus of the Carbon Chain
M. Sekido, K. Aoyagi, H. Nakamura, C. Kabuto, Y. Yamamoto, J. Org. Chem. 66, 7142-7147 (2001). LINK
[51] Fluorous Triphasic Reactions: Transportative Deprotection of Fluorous Silyl Ethers with Concomitant Purification.
H. Nakamura, B. Linclau, D. P. Curran, J. Am. Chem. Soc. 123, 10119-10120 (2001). LINK
[50] ortho-Carboranyl Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy
L. F. Tietze, U. Bothe, U. Griesbach, M. Nakaichi, T. Hasegawa, H. Nakamura, Y. Yamamoto, Bioorg. Med. Chem. 9, 1747-1752 (2001). LINK
[49] The Fate of Bis-p-allylpalladium Complexes in the Co-existence of Aldehydes (or Imines) and Allylic Chlorides. Stille Coupling versus Allylation of Aldehydes (or Imine).
H . Nakamura, B. Ming, Y. Yamamoto, Angew. Chem. Int. Ed. Engl. 40, 3208-3210 (2001). LINK
[48] Carboranyl Bisglycosides for the Treatment of Cancer by Boron Neutron Capture Therapy
L. F. Tietze, U. Bothe, U. Griesbach, M. Nakaichi, T. Hasegawa, H. Nakamura, Y. Yamamoto, ChemBioChem, 2, 326-334 (2001). LINK
[47] Facile Allylative Dearomatization Catalyzed by Palladium
B. Ming, H. Nakamura, Y. Yamamoto, J. Am. Chem. Soc. 123, 759-760 (2001). LINK
[46] Catalytic Amphiphilic Allylation via Bis-p-allylpalladium Complexes and Its Application to the Synthesis of Medium-Sized Carbocycles
H. Nakamura, K. Aoyagi, J. Shim, Y. Yamamoto, J. Am. Chem. Soc. 123, 372-377 (2001). LINK
[45] A Concise Synthesis of Chiral L-(4-Boronophenyl)alanine from L-Tyrosine
H. Nakamura, M. Fujiwara, Y. Yamamoto, Frontiers in Neutron Capture Therapy, Eds M. F. Hawthorn, K. Shelly, R. J. Wiersema, p765-768 Kluwer Academic/Plenum Publishers, New York (2001).
[44] In vitro Uptake Study of 5-Carboranyluridine and Its Derivatives
T. Hasegawa, M. Nakaichi, S. Nakama, H. Nakamura, Y. Yamamoto, M. Takagaki, A. Takeuchi, Frontiers in Neutron Capture Therapy, Eds M. F. Hawthorn, K. Shelly, R. J. Wiersema, p1003-1008 Kluwer Academic/Plenum Publishers, New York (2001).
[43] In Vivo Evaluation of Carborane Gadolinium-DTPA Complex as an MR Imaging Boron Carrier
H. Nakamura, H. Fukuda, F. Girard, T. Kobayashi, H. Nemoto, J. Cai, K. Yoshida, Y. Yamamoto, Chem. Pharm. Bull. 48, 1034-1038 (2000). LINK
[42] A Practical Method for the Synthesis of Enantiomerically Pure 4-Borono-L-phenylalanine
H. Nakamura, M. Fujiwara, Y. Yamamoto, Bull. Chem. Soc. Jpn. 73, 231-235 (2000). LINK
[41] Palladium Catalyzed Cyanoallylation of Activated Olefins
H. Nakamura, H. Shibata, Y. Yamamoto. Tetrahedron Lett. 41, 2911-2914 (2000). LINK
[40] Preparation and application of polymer-supported chiral p-allylpalladium catalyst for the allylation of imines.
B. Ming, H. Nakamura, Y. Yamamoto, Tetrahedron Lett. 41, 131-134 (2000).LINK
[39] Palladium(0) Catalyzed Cope Rearrangement of Acyclic 1,5-Dienes. Bis(p-allyl)palladium(II) Intermediate
H. Nakamura, H. Iwama, M. Ito, Y. Yamamoto, J. Am. Chem. Soc. 121 10850-10851 (1999). LINK
[38] Synthesis of a New Amphiphilic ortho-Carborane Derivative as a Potential BNCT Agent: 4-[N,N-Formyl-(ortho-carboranylmethyl)-amino]-benzoyl-L-glutamic Acid
K.-Y. Rho, Y.-J. Cho, C.-M. Yoon, H. Nakamura, Tetrahedron Lett. 40, 4821-4824 (1999). LINK
[37] A Concise and Stereospecific One-Shot Synthesis of Bicyclo[3,3,1]nonenols from Dimethyl 1,3-Acetonedicarboxylate and Enals via the Sequential Michael Addition-Intramolecular Aldolization
K. Aoyagi, H. Nakamura, Y. Yamamoto, J. Org. Chem. 64, 4148-4151 (1999). LINK
[36] Chiral p-Allylpalladium-Catalyzed Asymmetric Allylation: Replacement Allylstannanes by Allylsilanes.
K. Nakamura, H. Nakamura, Y. Yamamoto, J. Org. Chem. 64, 2614-2615 (1999).LINK
[35] Novel Addition Reactions of Silyl- and Stannyl-ortho-carboranes to Carbonyl Compounds
H. Nakamura, Y. Yamamoto, Collect. Czech. Chem. Commun. 64, 829-846 (1999). LINK
[34] The Synthesis of Carborane Gadolinium-DTPA Complex for Boron Neutron Capture Therapy
H. Nemoto, J. Cai, H. Nakamura, M. Fujiwara, Y. Yamamoto, J. Organomet. Chem. 581, 170-175 (1999). LINK
[33] Synthetic Utility of o-Carborane: Novel Protective Group for Aldehydes and Ketones.
H. Nakamura, K. Aoyagi, Y. Yamamoto, J. Organomet. Chem. 574, 107-115 (1999). LINK
[32] Relaxation properties of a dual-labeled probe for MRI and neutron capture therapy
A. T. Tatham, H. Nakamura, E. C. Wiener, Y. Yamamoto, Mag. Res. Med. 42, 32-36 (1999). LINK
[31]

The Renaissance of p-Allylpalladium-catalyzed Organic Synthesis.
H. Nakamura, Y. Yamamoto, J. Syn. Org. Chem. Jpn. 56, 395-405（1998）.

[30]

Palladium Catalyzed Regioselective b-Acetonation-a-Allylation of Activated Olefins in One Shot.
J.-G. Shim, H. Nakamura, Y. Yamamoto, J. Org. Chem. 63, 8470-8474 (1998).LINK

[29]

A Concise Synthesis of Enantiomerically Pure L-(4-Boronophenyl)alanine from L-Tyrosine
H. Nakamura, M. Fujiwara, Y. Yamamoto, J. Org. Chem. 63, 7529-7530 (1998). LINK
[28]

Palladium-Catalyzed Alkoxyallylation of Activated Olefins
H. Nakamura, M. Sekido, M. Ito, Y. Yamamoto, J. Am. Chem. Soc. 120, 6838-6839 (1998). LINK
[27]

Catalytic Asymmetric Allylation of Imines via Chiral Bis-p-allylpalladium Complexes.
H. Nakamura, K. Nakamura, Y. Yamamoto, J. Am. Chem. Soc. 120, 4242-4243 (1998). LINK
[26]

Tetrabutylammonium Fluoride Promoted Novel Reactions of o-Carborane: Inter- and Intramolecular Additions to Aldehydes and Ketones and Annulation via Enals and Enones
H. Nakamura, K. Aoyagi, Y. Yamamoto, J. Am. Chem. Soc. 120, 1167-1171 (1998). LINK
[25]

Amphiphilic Catalytic Allylating Reagent, Bis-p-allylpalladium Complex
H. Nakamura, J-G. Shim, Y. Yamamoto, J. Am. Chem. Soc. 119, 8113-8114 (1997). LINK
[24]

Synthesis of Carboranes Containing Azulene Framework and In vitro Evaluation as Boron Carriers.
H. Nakamura, M. Sekido, Y. Yamamoto, J. Med. Chem. 40, 2825-2830 (1997). LINK
[23] o-Carborane as a Novel Protecting Group of Aldehydes and Ketones.
H. Nakamura, K. Aoyagi, Y. Yamamoto, J. Org. Chem. 62, 780-781 (1997). LINK
[22] A Novel [3+2] Annulation between o-Carboranyltrimethylsilane and Conjugated Carbonyl Compounds
H. Nakamura, K. Aoyagi, B. Singaram, J. Cai, H. Nemoto, Y. Yamamoto, Angew. Chem. Int. Ed. Engl. 36, 367-369 (1997). LINK
[21] Tetrabutylammonium Fluoride Promoted Regiospecific Reaction of Trimethylsilyl-o-carborane with Carbonyl Compounds.
J. Cai, H. Nemoto, H. Nakamura, B. Singaram, Y. Yamamoto, Advances in Boron Chemistry, Ed. W. Siebert, p112-115, The Royal Society of Chemistry (1997).
[20] Rat Tumor Imaging with B-10 Carborane Gadolinium Complex.
F. Girard, H. Nakamura, H. Fukuda, Y. Yamamoto, K, Yoshida, Recent Advances in Biomedical Imaging, Ed. Y. Ishii et al., p201-207, Elsevier Science (1997).
[19] Synthesis of Carborane Containing Azlene Framework Using New Palladium Catalyzed Reaction.
H. Nakamura, M. Sekido, Y. Yamamoto, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, p42-45, Plenum Press, New York (1997).
[18] MR Imaging of Rat Tumor with 10B Carborane Gadolinium Complex.
F. Girard, H. Fukuda, H. Nakamura, Y. Yamamoto, K. Yoshida, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, p271-275, Plenum Press, New York (1997).
[17] A New Synthetic Method of All Carboxylate-free DTPA Derivatives and Its Application to the Synthesis of Gd-Carborane Complex.
Y. Yamamoto, J. Cai. H. Nemoto, H. Nakamura, F. Girard, K. Yoshida, H. Fukuda, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, p436-439, Plenum Press, New York (1997).
[16] Tetrabutylammonium Fluoride Promoted Regiospecific Reactions of Trimethylsilyl-o-Carborane with Aldehydes.
J. Cai, H. Nemoto, H. Nakamura, B. Singaram, Y. Yamamoto, Chem. Lett. 9, 791-792 (1996). LINK
[15] Palladium and Platinum Catalyzed Addition of Aldehydes and Imines with Allylstannanes. Chemoselective Allylation of Imines in the Presence of Aldehydes
H. Nakamura, H. Iwama, Y. Yamamoto, J. Am. Chem. Soc. 118, 6641-6647 (1996). LINK
[14] Unprecedented Highly Chemoselective Allylation of Imines in the Presence of Aldehydes via Palladium Catalyzed Allylstannane Reaction.
H. Nakamura, H. Iwama, Y. Yamamoto, Chem. Commun. 1459-1460(1996). LINK
[13] Netropsin and Distamycin Analogues Bearing ortho-Carborane
Y. Yamamoto, J. Cai, H. Nakamura, N. Sadayori, H. Nemoto, Cancer Neutron Capture Therapy, Ed. Y. Mishima, 177-182, Plenum Press, New York (1996).
[12] Palladium and Platinum-catalyzed Addition of Aldehydes with Allylstannanes.
H. Nakamura, N. Asao, Y. Yamamoto, J. Chem. Soc. Chem. Commun. 1273-1274 (1995). LINK
[11] Synthesis of Netropsin and Distamycin Analogues Bearing o-Carborane and Their DNA Recognition.
Y. Yamamoto, J. Cai, H. Nakamura, N. Sadayori, N. Asao, H, Nemoto, J. Org. Chem. 60, 3352-3357 (1995). LINK
[10] Palladium Catalyzed Addition of 1-Carboranyltributyltin to Aldehydes.
H. Nakamura, N. Sadayori, M. Sekido, Y. Yamamoto, J. Chem. Soc. Chem. Commun. 22581-2582 (1994).LINK
[9] Synthesis of New 10B Carriers and Their Selective Uptake by Cancer Cells.
Y. Yamamoto, H. Nemoto, H. Nakamura, S. Iwamoto, Current Topics in the Chemistry of Boron, Ed. G. Kabalka, p149-154, The Royal Society of Chemistry (1994).
[8] Synthesis and Biological Properties of Carboranylaziridine.　
Y. Yamamoto, H. Nakamura, H. Nemoto, Advances in Neutron Capture Therapy, Eds. A.H. Soloway, R.F. Barth, D.E. Carpenter, 305-308, Plenum Press, New York (1993).
[7] 1-Carboranyl-3-methylaziridino-2-propanol. Synthesis, Selective Uptake by B-16 Melanoma, and Selective Cytotoxicity toward Cancer Cells.
Y. Yamamoto, H. Nakamura, J. Med. Chem. 36, 2232-2234 (1993).LINK
[6] Regio- and Stereo-selective Ring Opening of Epoxides with Amide Cuprate Reagents.
Y. Yamamoto, N. Asao, M. Meguro, N. Tsukada, H. Nemoto, S. Sadayori, J. Gerald Wilson, H. Nakamura, J. Chem. Soc. Chem. Commun. 1201-1203 (1993).LINK
[5] Boron-11 NMR of Boron Compounds in the Presence of Cancer Cells.
Y. Yamamoto, S. Takamatsu, H. Nakamura, J. Magn. Res. Series B, 101, 198-200 (1993).LINK
[4] A New Water-soluble p-Boronophenylalanine Derivative for Neutron Capture Therapy.
H. Nemoto, S. Iwamoto, H. Nakamura, Y. Yamamoto, Chem. Lett. 465-468 (1993).LINK
[3] Synthesis of Carboranes Containing Nucleoside Bases.
Y. Yamamoto, T. Seko, H. Nakamura, H. Nemoto, Heteroatom Chem. 3, 239-244 (1992).LINK
[2] Polyols of a Cascade Type as a Water-Solubilizing Element of Carborane Derivatives for Boron Neutron Capture Therapy.
H. Nemoto, J. G. Wilson, H. Nakamura, Y. Yamamoto, J. Org. Chem. 57, 435 (1992). LINK
[1] Synthesis of Carboranes Containing Nucleoside Bases. Unexpectedly High Cytostatic and Cytocidal Toxicity toward Cancer Cells.
Y. Yamamoto, T. Seko, H. Nakamura, H. Nemoto, H. Hojo, N. Mukai, Y. Hashimoto, J. Chem. Soc. Chem. Commun. 157-158 (1992).LINK