原著論文


80. T. Takei, K. Tsumoto, M. Yoshino, S. Kojima, K. Yazaki, T. Ueda, T. Takei, F. Arisaka, K. Miura
"Role of Positions e and g in the Fibrous Assembly Formation of an Amphipathic α-helix-forming Polypeptide"
Biopolymers (Peptide Science) 102(3), 260-272 (2014)

79. T.Tsuda, M. Asami, Y. Koguchi, S. Kojima
"A Single Mutation Alters the Substrate Specificity of L-amino acid Ligase"
Biochemistry 53(16), 2650-2660 (2014)

78. T. Takei, K. Hasegawa, K. Imada, K. Namba, K. Tsumoto, Y. Kuriki, M. Yoshino, K. Yazaki, S. Kojima, T. Takei, T. Ueda, K. Miura
"Effects of Chain Length of an Amphipathic Polypeptide Carrying the Repeated Amino Acid Sequence (LETLAKA)n on α-helix and Fibrous Assemby Formation"
Biochemistry. 52(16), 2810-2820 (2013)

77. T. Tsuda, T. Suzuki, S. Kojima
"Crystallization and Preliminary X-ray Diffraction Analysis of Bacillus subtilis YwfE, an L-amino-acid Ligase"
Acta Crystal. F68(2), 203-206 (2012)

76. H. Hemmi, T. Kumazaki, S. Kojima, T. Yoshida, T. Ohkubo, H. Yokosawa, K. Miura, Y. Kobayashi
"Increasing the Hydrolysis Constant of the Reactive Site upon Intrduction of an Engineered Cys14-Cys35 Bond into the Ovomucoid Third Domain from Silver Pheasant
"
J. Peptide Sci. 17(8), 595-600 (2011)

75. N. Shibata, Y. Ueda, D. Takeuchi, Y. Haruyama, S. Kojima, J. Sato, Y. Niimura, M. Kitamura, Y. Higuchi
"Structure Analysis of the Flavoredoxin from Desulfovibrio vulgaris Miyazaki F Reveals Key Residues That Discriminate the Functions and Properties of Flavin Reductase Family"
FEBS J. 276(17), 4840-4853 (2009)

74. G. Aoki, T.K. Yamada, M. Arii, S. Kojima, T. Mizoguchi
"Requirement of Ala Residues at g Position in Heptad Sequence of α-helix-forming Peptide for Formation of Fibrous Structurey"
J. Biochem. 144(1), 15-19 (2008)

73. S. Kojima, A. Iwahara, Y. Hisano, H. Yanai
"Effects of Hydrophobic Amino Acid Substitution in Pleurotus ostreatus Proteinase A Inhibitor 1 on Its Structure and Functions as Protease Inhibitor and Intramolecular Chaperone"
Protein Engng. Des. Sel. 20(5), 211-217 (2007)

72. T. Takei, A. Okonogi, K. Tateno, A. Kimura, S. Kojima, K. Yazaki, K. Miura
"The Effects of the Side Chains of Hydrophobic Aliphatic Amino Acid Residues in an Amphipathic Polypeptide on the Formation of α Helix and Its Association"
J. Biochem. 139(2), 271-278 (2006)

71. S. Ichiyama, Y. Oka, K. Haga, S. Kojima, Y. Tateishi, M. Shirakawa, T. Haga
"The Structure of the Third Intracellular Loop of the Muscarinic Acetylcholine Receptor M2 Subtype"
FEBS Lett. 580(1), 23-26 (2006)

70. S. Kojima, A. Iwahara, H. Yanai
"Inhibitor-Assisted Refolding of Protease: A Protease Inhibitor as an Intramolecular Chaperone"
FEBS Lett. 579(20), 4430-4436 (2005)

69. S. Kojima, Y. Kuriki, K. Yazaki, K. Miura
"Stabilization of the Fibrous Structure of an
α-Helix-Forming Peptide by Sequence Reversal"
Biochem. Biophys. Res. Commun. 331(2), 577-582 (2005)

68. S. Tanaka, S. Kojima, A. Tamura
"Mapping the Position of the Transition State in the Folding of a Small
α/β Protein, POIA1"
Chem. Phys. 307(2/3), 233-242 (2004)

67. M. Motizuki, T. Takei, K. Tasaka, S. Yokota, S. Kojima, T. Haga, K. Tsurugi
"Low pH Facilitates Uptake of Proteins by Cells through a Non-Endocytic Pathway"
J. Biochem. 135(6), 713-719 (2004)

66. M. Kitamura, Y. Takayama, S. Kojima, K. Kohno, H. Ogata, Y. Higuchi, H. Inoue
"Cloning and Expression of the Enolase Gene from Desulfovibrio vulgaris (Miyazaki F)"
Biochim. Biophys. Acta 1676(2), 172-181 (2004)

65. H. Hemmi, T. Kumazaki, T. Yamazaki, S. Kojima, T. Yoshida, Y. Kyogoku, M. Katsu, F. Shinohara, H. Yokosawa, K. Miura, Y. Kobayashi
"Inhibitory Specificity Change of the Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond "
Biochemistry 42(9), 2524-2534 (2003)

64. M. Oda, A. Tamura, K. Kanaori, S. Kojima, K. Miura, K. Momma, B. Tonomura, K. Akasaka
"Functional Tolerance of Streptomyces Subtilisin Inhibitor toward Conformational and Stability Changes Caused by Single-Point Mutations in the Hydrophobic Core "
J. Biochem., 132(6), 991-995 (2002)

63. M. Motizuki, T. Satoh, T. Takei, T. Itoh, S. Yokota, S. Kojima, K. Miura, T. Samejima, K. Tsurugi
"Structure-Activity Analysis of an Antimicrobial Peptide Derived from Bovine Apolipoprotein A-II "
J. Biochem., 132(1), 115-119 (2002)

62. S. Kojima, Y. Hisano
"Requirement for Hydrophobic Phe Residues in Pleurotus ostreatus proteinase A Inhibitor 1 for Stable Inhibition "
Protein Engng., 15(4), 325-329 (2002)

61. H. Sasagawa, S. Yoshinaga, S. Kojima, A. Tamura
"Structure of POIA1, a Homologous Protein to the Propeptide of Subtilisin: Implication for Protein Stability and the Function as an Intramolecular Chaperone "
J. Mol. Biol., 317(1), 159-167 (2002)

60. S. Kojima, H. Yanai, K. Miura
"Accelerated Refolding of Subtilisin BPN
by Tertiary-Structure-Forming Mutants of Its Propeptide "
J. Biochem., 130(4), 471-474 (2001
)

59. S. Kojima, Y. Hisano, K. Miura
"Alteration of Inhibitory Properties of Pleurotus ostreatus Proteinase A Inhibitor 1 by Mutation of Its C-Terminal Region"
Biochem. Biophys. Res. Commun., 281(5), 1271-1276 (2001)

58. M. Kitamura, T. Nakanishi, S. Kojima, I. Kumagai, H. Inoue
"Cloning and Expression of the Catalase Gene from the Anaerobic Bacterium Desulfovibrio vulgaris (Miyazaki F) "
J. Biochem., 129(3), 357-364 (2001)

57. M. Wakiyama, A. Suzuki, M. Saigoh, N. Sakai, H. Miyoshi, S. Kojima, K. Miura
"Analysis of the Isoform of Xenopus Eukaryotic Translation Initiation Factor 4E"
Biosci. Biotech. Biochem., 65(1), 232-235 (2001)

56. S. Kojima, N. Takagi, T. Minagawa, N. Fushimi, K. Miura
"Effects of Amino Acid Replacements around the Reactive Site of Chicken Ovomucoid Domain 3 on the Inhibitory Activity toward Chymotrypsin and Trypsin"
Protein Engng., 12(10), 857-862 (1999)

55. H. Sato, K. Akama, S. Kojima, K. Miura, A. Sekine, M. Nakano
"Expression of a Zinc-Binding Domain of Boar Spermatidal Transition Protein 2 in Escherichia coli"
Protein Express. Purif., 16(3),
 454-462 (1999)

54. S. Kojima, M. Deguchi, K. Miura
"Involvement of the C-Terminal Region of Yeast Proteinase B Inhibitor 2 in Its Inhibitory Action"
J. Mol. Biol., 286(3), 775-785 (1999)

53. D. Nohara, H. Sugiura, H. Sakakibara, M. Matsubara, S. Kojima, K. Miura, T. Sakai
"High Performance in Refolding of Streptomyces griseus Trypsin by the Aid of a Mutant of Streptomyces Subtilisin Inhibitor Designed as Trypsin Inhibitor"
J. Biochem., 125(2), 343-347 (1999)

52. T. Tanaka, H. Matsuzawa, S. Kojima, I. Kumagai, K. Miura, T. Ohta
"P1-Specificity of Aqualysin I (a Subtilisin-Type Serine Protease) from Thermus aquaticus YT-1, Using P1-Substituted Derivatives of Streptomyces Subtilisin Inhibitor"
Biosci. Biotech. Biochem., 62(10), 2035-2038 (1998)

51. S. Taguchi, S. Yamada, S. Kojima, H. Momose
"An Endogenous Target Protease, SAM-P26, of Streptomyces Protease Inhibitor (SSI): Primary Structure, Enzymatic Characterization, and Its Interaction with SSI"
J. Biochem., 124(4), 804-810 (1998)

50. S. Kojima, T. Kumazaki, S. Ishii, K. Miura
"Primary Structure of Streptomyces griseus Metalloendopeptidase II"
Biosci. Biotech. Biochem., 62(7), 1392-1398 (1998)

49. M. Kitamura, T. Sagara, M. Taniguchi, M. Ashida, K. Ezoe, K. Kohno, S. Kojima, K. Ozawa, H. Akutsu, I. Kumagai, T. Nakaya
"Cloning and Expression of the Gene Encoding Flavodoxin from Desulfovibrio vulgaris (Miyazaki F)"
J. Biochem., 123(5), 891-898 (1998)

48. S. Kojima, T. Minagawa, K. Miura
"Tertiary Structure Formation in the Propeptide of Subtilisin BPN' by Successive Amino Acid Replacements and Its Close Relation to Function"
J. Mol. Biol., 277(5), 1007-1013 (1998)

47. S. Kojima, T. Minagawa, K. Miura
"The Propeptide of Subtilisin BPN' as a Temporary Inhibitor and Effect of an Amino Acid Replacement on Its Inhibitory Activity"
FEBS Lett., 411(1), 128-132 (1997)

46. M. Wakiyama, N. Sakai, S. Kojima, K. Miura
"Disulfide Bond Formation Is Not Involved in Cap-Binding Activity of Xenopus Translation Initiation Factor eIF-4E"
FEBS Lett., 409(3), 407-410 (1997)

45. S. Taguchi, S. Kojima, M. Terabe, Y. Kumazawa, H. Kohriyama, M. Suzuki, K. Miura, H. Momose
"Molecular Phylogenetic Characterization of Streptomyces Protease Inhibitor Family"
J. Mol. Evol., 44(5), 542-551 (1997)

44. M. Kitamura, Y. Koshino, Y. Kamikawa, K. Kohno, S. Kojima, K. Miura, T. Sagara, H. Akutsu, I. Kumagai, T. Nakaya
"Cloning and Expression of the Rubredoxin Gene from Desulfovibrio vulgaris (Miyazaki F)--Comparison of the Primary Structure of Desulfoferrodoxin"
Biochim. Biophys. Acta, 1351(1/2), 239-247 (1997)

43. S. Kojima, Y. Kuriki, T. Yoshida, K. Yazaki, K. Miura
"Fibril Formation by an Amphipathic
α-Helix-Forming Polypeptide Produced by Gene Engineering"
Proc. Japan Acad., 73B(1), 7-11 (1997)

42. M. Suzuki, S. Taguchi, S. Yamada, S. Kojima, K. Miura, H. Momose
"A Novel Member of the Subtilisin-Like Protease Family from Streptomyces albogriseolus"
J. Bacteriol., 179(2), 430-438 (1997)

41. S. Kojima, K. Miyoshi, K. Miura
"Synthesis of a Squash-Type Protease Inhibitor by Gene Engineering and Effects of Replacements of Conserved Hydrophobic Amino Acid Residues on Its Inhibitory Activity"
Protein Engng., 9(12), 1241-1246 (1996)

40. S. Kojima, Y. Kuriki, Y. Sato, F. Arisaka, I. Kumagai, S. Takahashi, K. Miura
"Synthesis of
α-Helix-Forming Peptides by Gene Engineering Methods and Their Characterization by Circular Dichroism Spectra Measurements"
Biochim. Biophys. Acta, 1294(2), 129-137 (1996)

39. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura
"New Subtilisin-Trypsin Inhibitors Produced by Streptomyces: Primary Structures and Their Relationship to Other Proteinase Inhibitors from Streptomyces"
Biochim. Biophys. Acta, 1292(2), 233-240 (1996)

38. A. Tamura, M. Matsushita, A. Naito, S. Kojima, K. Miura, K. Akasaka
"Dynamics of the Three Methionyl Side Chains of Streptomyces Subtilisin Inhibitor. Deuterium NMR Studies in Solution and in the Solid State"
Protein Sci., 5(1), 127-139 (1996)

37. S. Taguchi, S. Kojima, K. Miura, H. Momose
"Taxonomic Characterization of Closely Related Streptomyces spp. Based on the Amino Acid Sequence Analysis of Protease Inhibitor Proteins"
FEMS Microbiol. Lett., 135(2/3), 169-173 (1996)

36. S. Taguchi, M. Suzuki, S. Kojima, K. Miura, H. Momose
"Streptomyces Serine Protease (SAM-P20): Recombinant Production, Characterization, and Interaction with Endogenous Protease Inhibitor"
J. Bacteriol., 177(22), 6638-6643 (1995)

35. K. Akama, H. Ichimura, H. Sato, S. Kojima, K. Miura, H. Hayashi, Y. Komatsu, M. Nakano
"The Amino Acid Sequence and Interaction with the Nucleosome Core DNA of Transition Protein 4 from Boar Late Spermatid Nuclei"
Eur. J. Biochem., 233(1), 179-185 (1995)

34. A. Tamura, S. Kojima, K. Miura, J. M. Sturtevant
"A Thermodynamic Study of Mutant Forms of Streptomyces Subtilisin Inhibitor. II. Replacements at the Interface of Dimer Formation, Val13"
J. Mol. Biol., 249(3), 636-645 (1995)

33. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura
"A Subtilisin Inhibitor Produced by Streptomyces bikiniensis Possesses a Glutamine Residue at Reactive Site P1"
J. Biochem., 117(3), 609-613 (1995)

32. A. Tamura, S. Kojima, K. Miura, J. M. Sturtevant
"Effect of an Intersubunit Disulfide Bond on the Stability of Streptomyces Subtilisin Inhibitor"
Biochemistry, 33(48), 14512-14520 (1994)

31. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura
"Primary Structure and Inhibitory Properties of a Subtilisin-Chymotrypsin Inhibitor from Streptomyces virginiae"
Eur. J. Biochem., 226(2), 627-632 (1994)

30. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura
"Three Novel Subtilisin-Trypsin Inhibitors from Streptomyces: Primary Structures and Inhibitory Properties"
J. Biochem., 116(5), 1156-1163 (1994)

29. T. Hayashi, M. Matsubara, D. Nohara, S. Kojima, K. Miura, T. Sakai
"Renaturation of the Mature Subtilisin BPN' Immobilized on Agarose Beads"
FEBS Lett., 350(1), 109-112 (1994)

28. S. Kojima, M. Terabe, S. Taguchi, H. Momose, K. Miura
"Primary Structure and Inhibitory Properties of a Proteinase Inhibitor Produced by Streptomyces cacaoi"
Biochim. Biophys. Acta, 1207(1), 120-125 (1994)

27. S. Kojima, N. Fushimi, A. Ikeda, I. Kumagai, K. Miura
"Secretory Production of Chicken Ovomucoid Domain 3 by Escherichia coli and Alteration of Inhibitory Specificity toward Proteases by Substitution of the P1 Site Residue"
Gene, 143(2), 239-243 (1994)

26. T. Tange, S. Taguchi, S. Kojima, K. Miura, H. Momose
"Improvement of a Useful Enzyme (Subtilisin BPN') by an Experimental Evolution System"
Appl. Environ. Microbiol., 41(2), 239-244 (1994)

25. M. Matsubara, E. Kurimoto, S. Kojima, K. Miura, T. Sakai
"Achievement of Renaturation of Subtilisin BPN' by a Novel Procedure Using Organic Salts and a Digestible Mutant of Streptomyces Subtilisin Inhibitor"
FEBS Lett., 342(2), 193-196 (1994)

24. S. Taguchi. S. Kojima, M. Terabe, K. Miura, H. Momose
"Comparative Studies on the Primary Structures and Inhibitory Properties of Subtilisin-Trypsin Inhibitors from Streptomyces"
Eur. J. Biochem., 220(3), 911-918 (1994)

23. K. Akama, S. Kojima, M. Nakano, T. Tobita, H. Hayashi
"The Amino Acid Sequence and Phosphorylation Sites of a Boar Transition Protein 1"
Biochem. Mol. Biol. Int., 32(2), 349-357 (1994)

22. M. Kitamura, S. Kojima, K. Ogasawara, T. Nakaya, T. Sagara, K. Niki, K. Miura, H. Akutsu, I. Kumagai
"Novel FMN-Binding Protein from Desulfovibrio vulgaris (Miyazaki F)--Cloning and Expression of Its Gene in Escherichia coli"
J. Biol., Chem., 269(8), 5566-5573 (1994)

21. S. Kojima, K. Fujimura, I. Kumagai, K. Miura
"Contribution of Salt Bridge in the Protease Inhibitor SSI (Streptomyces Subtilisin Inhibitor) to Its Inhibitory Action"
FEBS Lett., 337(2), 195-199 (1994)

20. S. Taguchi, H. Kikuchi, M. Suzuki, S. Kojima, M. Terabe, K. Miura, T. Nakase, H. Momose
"Streptomyces Subtilisin Inhibitor-Like Proteins Are Distributed Widely in Streptomycetes"
Appl. Environ. Microbiol., 59(12), 4338-4341 (1993)

19. K. Masuda-Momma, T. Shimakawa, K. Inouye, K. Hiromi, S. Kojima, I. Kumagai, K. Miura, B. Tonomura
"Identification of Amino Acid Residues Responsible for the Changes of Absorption and Fluorescence Spectra on the Binding of Subtilisin BPN' and Streptomyces Subtilisin Inhibitor"
J. Biochem., 114(6), 906-911 (1993)

18. M. Matsubara, E. Kurimoto, S. Kojima, K. Miura, T. Sakai
"Quantitative in vitro Renaturation of Subtilisin BPN' without the Aid of Pro-Sequence"
Chem. Lett., 1993(10), 1783-1786 (1993)

17. T. Kumazaki, K. Kajiwara, S. Kojima, K. Miura, S. Ishii
"Interaction of Streptomyces Subtilisin Inhibitor (SSI) with Streptomyces griseus Metallo-Endopeptidase II (SGMP II)"
J. Biochem., 114(4), 570-575 (1993)

16. K. Masuda-Momma, T. Hatanaka, K. Inouye, K. Kanaori, A. Tamura, K. Akasaka, S. Kojima, I. Kumagai, K. Miura, B. Tonomura
"Interaction of Subtilisin BPN' and Recombinant Streptomyces Subtilisin Inhibitors with Substituted P1 Site Residues"
J. Biochem., 114(4), 553-559 (1993)

15. M. Kitamura, K. Ozawa, S. Kojima, I. Kumagai, H. Akutsu, K. Miura
"The Primary Structure of Pre-Cytochrome c3 from Desulfovibrio vulgaris (Miyazaki F) as Determined by Necleotide Sequencing of Its Gene and Partial Amino Acid Sequencing"
Protein Seq. Data Anal., 5(5), 193-196 (1993)

14. S. Kojima, S. Furukubo, I. Kumagai, K. Miura
"Effects of Deletion in the Flexible Loop of the Protease Inhibitor SSI (Streptomyces Subtilisin Inhibitor) on Interactions with Proteases"
Protein Engng., 6(3), 297-303 (1993)

13. S. Kojima, I. Kumagai, K. Miura
"Requirement for a Disulfide Bridge near the Reactive Site of Protease Inhibitor SSI (Streptomyces Subtilisin Inhibitor) for Its Inhibitory Action"
J. Mol. Biol., 230(2), 395-399 (1993)

12. S. Taguchi, H. Kikuchi, S. Kojima, I. Kumagai, T. Nakase, K. Miura, H. Momose
"High Frequency of SSI-like Protease Inhibitors among Streptomyces"
Biosci. Biotech. Biochem., 57(3), 522-524 (1993)

11. S. Taguchi, S. Kojima, I. Kumagai, H. Ogawara, K. Miura, H. Momose
"Isolation and Partial Characterization of SSI-like Protease Inhibitors from Streptomyces"
FEMS Microbiol. Lett., 99(2/3), 293-297 (1992)

10. Y. Ueda, S. Kojima, K. Tsumoto, S. Takeda, K. Miura, I. Kumagai
"A Protease Inhibitor Produced by Streptomyces lividans 66 Exhibits Inhibitory Activities toward Both Subtilisin BPN' and Trypsin"
J. Biochem., 112(2), 204-211 (1992)

9. Y. Takeuchi, T. Nonaka, K. T. Nakamura, S. Kojima, K. Miura, Y. Mitsui
"Crystal Structure of an Engineered Subtilisin Inhibitor Complexed with Bovine Trypsin"
Proc. Natl. Acad. Sci. U.S.A., 89(10), 4407-4411 (1992)

8. Y. Takeuchi, S. Noguchi, Y. Satow, S. Kojima, I. Kumagai, K. Miura, K. T. Nakamura, Y. Mitsui
"Molecular Recognition at the Active Site of Subtilisin BPN': Crystallographic Studies Using Genetically Engineered Proteinaceous Inhibitor SSI (Streptomyces Subtilisin Inhibitor)"
Protein Engng., 4(5), 501-508 (1991)

7. A. Tamura, K. Kanaori, S. Kojima, I. Kumagai, K. Miura, K. Akasaka
"Mechanisms of Temporary Inhibition in Streptomyces Subtilisin Inhibitor Induced by an Amino Acid Substitution, Tryptophan 86 Replaced by Histidine"
Biochemistry, 30(21),

6. S. Kojima, Y. Nishiyama, I. Kumagai, K. Miura
"Inhibition of Subtilisin BPN' by Reaction Site P1 Mutants of Streptomyces Subtilisin Inhibitor"
J. Biochem., 109(3), 377-382 (1991)

5. S. Kojima, I. Kumagai, K. Miura
"Effect on Inhibitory Activity of Mutation at Reaction Site P4 of the Streptomyces Subtilisin Inhibitor, SSI"
Protein Engng., 3(6), 527-530 (1990)

4. S. Kojima, S. Obata, I. Kumagai, K. Miura
"Alteration of the Specificity of the Streptomyces Subtilisin Inhibitor by Gene Engineering"
Bio/Technology, 8(5), 449-452 (1990)

3. K. Miura, I. Kumagai, S. Obata, S. Kojima, S. Taguchi
"Partial Alteration of a Protein Streptomyces Subtilisin Inhibitor by Site-Directed Mutagenesis"
Proc. Japan Acad., 64B(6), 147-149 (1988)

2. I. Kumagai, S. Kojima, E. Tamaki, K. Miura
"Conversion of Trp62 of Hen Egg-White Lysozyme to Tyr by Site-Directed Mutagenesis"
J. Biochem., 102(4), 733-740 (1987)

1. T. Tobita, H. Tanaka, K. Tanaka, T. Tanaka, S. Kojima, M. Nakano
"Characteristics of Cysteinyl Sulfhydryls and Nuclease Sensitivity of Boar Sperm Nuclei during Epididymal Maturation"
Biochem. Int., 9(2), 161-168 (1984)



英文著書

1. Protein Engineering (M. Ikehara, ed.)
Y. Takeuchi, S. Noguchi, Y. Satow, S. Kojima, I. Kumagai, K. Miura, Y. Mitsui
"Molecular Recognition at the Interface between Subtilisin BPN' and Its Proteinaceous Inhibitor SSI" pp103-108
S. Kojima, S. Furukubo, Y. Nishiyama, K. Fujimura, I. Kumagai, K. Miura
"Alteration of the Functional Structure of the Protease Inhibitor, Streptomyces Subtilisin Inhibitor by Site-Directed Mutagenesis" pp147-152
(Japan Scientific Society Press & Springer-Verlag, 1990)



邦文著書・総説

18.
小島修一、三浦謹一郎
   廣川タンパク質化学 第7巻 制御タンパク質−インヒビター
    36 ズブチリシンインヒビター、191-196
     (廣川書店、20025月)

17.
小島修一、三浦謹一郎
   プロペプチドおよびプロテアーゼインヒビターによるプロテアーゼのフォールディング
    蛋白質核酸酵素、46, 1686-1691 (2001)

16.
小島修一
   プロテアーゼのプロペプチドの二面性:インヒビターおよび分子シャペロン
    バイオサイエンスとインダストリー、56(5)327-328 (1998)

15.
小島修一
   シリーズ分子生物学6 構造生物学 (三浦謹一郎編)
    4. タンパク質の多彩な機能と構造の関係
     4.6 プロテアーゼとインヒビター、131-144
     (朝倉書店、19981月)

14.
渡辺公綱、小島修一
   バイオテクノロジー教科書シリーズ9
    蛋白質工学概論
    (コロナ社、1995年7月)

13.
小島修一、三浦謹一郎
   蛋白質核酸酵素・臨時増刊 蛋白質の時代--構造・物性・機能研究の新局面
   (郷 信広、大島泰郎、油谷克英、猪飼 篤編)
    プロテアーゼの機能変換とプロテアーゼ・インヒビターの阻害機構、1111-1120頁 
    (共立出版、19945月)

12.
小島修一
    分子生物学(放送大学印刷教材、三浦謹一郎編)
     13章 タンパク質の構造と機能(1) 基礎 181-195
     14章 タンパク質の構造と機能(2) タンパク質工学 196-209
     (日本放送出版協会、19933月)

11.
小島修一
    精製分離技術ハンドブック(日本化学会編)
    II 編 応用編 13 バイオサイエンス
    13.7.5 遺伝子産物の分離精製、717-726
     13.7.6 DNAの構造解析、726-731
    (丸善、19933月)

10.
小島修一、三浦謹一郎
   新生化学実験講座 第1巻 タンパク質 VII タンパク質工学 (日本生化学会編)
    8. 研究例 8・1 ズブチリシンインヒビター、355-372
    (東京化学同人、19932月)

9.
小島修一
   バイオテクノロジー基礎講座 第2分冊 バイオテクノロジーの原理と応用
  (太田次郎、百瀬春生編)
    第4週 タンパク質工学、75-100
    (工学研究社、199210月)

8.
甲斐荘正恒、安倍未央、三宅洋子、小島修一
   蛋白質核酸酵素・臨時増刊 蛋白質工学の進展--蛋白質の設計をめざして
   (三浦謹一郎、京極好正、菊池正和、松浦良樹編)
    蛋白質の安定同位体利用NMRスペクトル、465-479
    (共立出版、19922月)

7.
小島修一、熊谷 泉、三浦謹一郎
   現代化学・増刊19 プロテインエンジニアリング (三浦謹一郎編)
    8. プロテアーゼインヒビターSSI、74-83
    (東京化学同人、19909月)

6.
プロテインエンジニアリング II (渡辺公綱、熊谷 泉編)
  小島修一、熊谷 泉
    第1編 タンパク質改変諸例
     第4章 その他のタンパク質の機能改変--プロテアーゼインヒビター、99-111
  小島修一、北村昌也
    付表 タンパク質・核酸改変データ、169-232
      (シーエムシー、19903月)

5.
小島修一、熊谷 泉、三浦謹一郎
   放線菌サブチリシンインヒビターの蛋白質工学
    蛋白質核酸酵素、34(8)939-948 (1989)

4.
小島修一、三浦謹一郎
   プロテアーゼ・インヒビターの人為的改変と分子進化
    遺伝、42(12)13-17 (1988)

3.
小島修一
   トピックス サブチリシンの基質補助触媒作用(Substrate-Assisted Catalysis)
   化学と工業、41(7)678-689 (1988

2.
小島修一、熊谷 泉
   新・酵素利用技術 (相沢益男編)
   メディカル編、第2章、酵素阻害剤、24-41
     (シーエムシー、19883月)

1.
小島修一、三浦謹一郎
   最近のタンパク質工学のトピックス
    化学、42(12)850-851 (1987)



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